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Hi, I'm coming from iphone 8 to iphone 11 and experienced the same thing you describe with your new iphone SE. There is a whole thread on iphone XR eye strain in Macrumors forum so you can visit it to read for more information (they also discuss other iphone models including your SE):
https://forums.macrumors.com/threads/eye-strain-on-iphonexr.2150554/page-21
In short, we suspect that after iphone 8/8 Plus, the XR and 11 start to use a different kind of display technology that is very fatiguing on the eyes (maybe they use dithering technology to reproduce colors?). The white color on the screen always have that pinky/yellowish/rainbow effect; it is not a solid and "static" white color like iphone 8. It has a "blinding" effect and very hard for our eyes to focus on, and there are no ways to fix that by any setting. If you are sensitive to that, just return it and find another phone.