I might be a bit late here, but I was just checking Ditherig.exe for updated versions, and it seems its been expanded to work on AMD APUs.
https://kawamoto.no-ip.org/henteko/myapp_en.html
This requires Intel 6th generation graphics or later (e.g. Intel HD Graphics 3000, including Sandy Bridge, Ivy Bridge, Haswell, Silvermont, Broadwell, Airmont, Skylake, Kaby Lake, Goldmont, Coffee Lake, Goldmont Plus, Amber Lake, Whiskey Lake, Ice Lake, Comet Lake, Lakefield, Tremont and Rocket Lake generations) or AMD GCN 5th generation graphics or later (e.g. AMD Radeon Vega 11 Graphics, including Raven Ridge, Picasso, Renoir and Cezanne generations).
I have checked behavior with the combinaion of Intel UHD Graphics 620 and NVIDIA GeForce MX150, Intel HD Graphics 515, Intel Iris Pro Graphics 5200, Intel HD Graphics 4000 and AMD Radeon Vega 8 Graphics.