I've always believed based on my experiences with some older (2013 to 2018) setups that the integrated graphics driver are a possible source of eyestrain. I have two laptops (one Intel, one AMD) that are very comfortable to look at when the Basic Display Adapter is being used (or when the hardware-specific Intel or AMD drivers are disabled), but not when the Intel (or AMD) drivers drivers are enabled. I don't play games so the performance-hit of the Basic Display adapter doesn't bother me.
But I'm wondering if this may not be true for some of the newer hardware, since I'm having symptoms with some newer machines or monitors even with hardware graphics drivers disabled. Does anyone have an opposite experience, where they felt better comfort with the hardware drivers enabled than with the Basic Display Adapter?