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Majority of users who used Macbooks with Asahi Linux installed did not feel abnormal eye strain
I believe that with Apple Silicon GPUs, the GPU driver is responsible for enabling dithering on the hardware. Asahi Linux, which initially didn’t have a GPU driver, might have been free from dithering-related issues. However, when I installed a version of Asahi Linux last year that included the GPU driver, I noticed it caused me more discomfort compared to macOS with StillColor.
Majority of users who used Macbooks with Windows installed did not feel abnormal eye strain
I haven't worked with Windows on a Mac, but I have worked with Linux on a Mac.
I am currently using the old TN 6bit+FRC monitor because I can't find a suitable replacement for it. Windows and Linux on this monitor are unusable, as is macOS on Intel-based Macs. However, the same version of macOS installed on a Mac with M1 allows me to work with this monitor for 10 hours or more with minimal breaks and almost no discomfort.
When using a TV with a true 8-bit display, I don't see any difference between macOS (Intel Mac, M1 Mac) and Linux (Intel Mac, PC with an Intel ARC GPU). They are all comfortable for the eyes.
In all cases here, dithering on the graphics card side is turned off, and the output is set to 8-bit.
Majority of users who used Macbooks with virtualised non Mac OS installed did not feel abnormal eye strain
I can use Windows with my 6bit+FRC monitor when it's running in Parallels on a MBP M1. In this case, Windows is very comfortable for the eyes, but in this setup, I also do not have any problems with macOS.
Let say we raise hypothesis that Mac OS (Software) Is a primary cause of eye strain within this community.
I think it's both the software and the hardware at the same time. Since software is closely intertwined with hardware. Windows, Linux, and macOS running on Apple hardware will use drivers that may differ from each other. Accordingly, dithering may be present in some cases and absent in others.
Moreover, we all have different levels of sensitivity in our eyes, and we may all have different causes for our issues. For example, many criticize the slightly blurred font in macOS. I use a 24" 1080p monitor with macOS, and it has never bothered me, at least up to and including Sonoma. But I know people whose eyes get very strained when reading text without subpixel smoothing.
Therefore, it is very difficult to determine the true cause of the problems, as there are too many free variables in this equation.