"Do you have any kind of setup that works?"
Not so far. I use a Macbook Air with an external Dell E2414 on 0% brightness, and external keyboard and mouse. I use a terminal hack to disable blinking cursors in NSText applications, but there's no fix for WebKit. I use Firefox or Waterfox and Thunderbird because they have their own settings to disable blinking cursors, and use NeoOffice instead of LibreOffice because it uses NSText so it works with the terminal hack. I use dozens of about:config fixes, add-ons, user styles, user scripts, and user css to try to block animation in FF and WF.
"If the site is static / static cursor. What's a example of a "good" website layout?"
It's relatively simple, with a single column, without background images, and if it includes position: fixed or position: sticky elements, they should be relatively narrow, without excess contrast, and particularly without scrolling cutting across patterns.
It may include clearly-marked videos if users want to play them (ironically I have less trouble with Youtube videos than with many web pages).
It works with page up/page down buttons, and doesn't animate the move.
It's not complex with multiple columns and/or blocks (if users need accessible fonts and/or larger sizes, these can make blocks overlap), background images, automatic animation or autoplaying videos, anything popping up or changing shape on scroll (many sticky headers do this), anything expanding on mouseover (many sites do this, it triggers my migraines), without tooltips popping up and blocking links or other options (internet archive does this with larger font sizes), without tooltips popping up under the cursor, disappearing, reappearing, and strobing 4 times per second (wikipedia sometimes does this with larger font sizes), and without links on the left side switching between two js_reel options 30 times per second (some other sites do this).
When Firefox's Reader View works, I find it is a good layout.