I figured I'd post a setup that seems to mostly work for me. They have them at my Campus Library so I don't have control over the details of the settings. But here is the info I do have.
Dell Precision 3460 with 13th Gen Intel(R) Core (TM) i7-13700 (2.10 GHz), 16GB of RAM and an Nvidia T1000.
Windows 11 Enterprise 26100.6584 Windows Feature Experience Pack 1000.26100.234.0.
Monitor is an Acer KG271u 27 inch 2560x1440 set to 59.95hz, SDR mode, 8 bit color. Dynamic refresh is off. Nvidia Driver version 31.0.15.5223.
The browser that has the least eye strain on this setup is Microsoft Edge.