I have been working last years on Ubuntu 14.04 LTS, but in next month there would be end of LTS and I'm looking new distibution for migration. I've already tried several Linux distibutions including Ubuntu 16.04 (Unity)/18.04 (Gnome) and Manjaro XFCE 18.0.4, but on all of them I got some kind of excitation/strain in head and eyes.
I've tried different options for "font hinting" and "antialiasing" but symptoms are same.
Which Linux distributions do you use now (or have used in past without any eye/head/led related problems)?
How did you configure your system and which hardware do you have?
Did you try to switch to modern/recent distributions?
My current configuration:
CPU - i7-7700K
GPU - AMD HD5450 + with open source drivers (xserver-xorg-video-radeon 1:7.3.0-1ubuntu3.1)
Display - Dell U2711 (CCFL)
Connection - DVI
OS - Ubuntu 14.04, Unity with default options
Kernel - 3.13.0-167-generic X86_64