I have the same symptoms like other users of this forum. When looking at newer displays (from 2016 on) I have aching, burning and tiring eyes with increasing tension to nausea and hypersensitivity. Headache has also increased recently. After just a few minutes of using, it often takes hours/days until the feeling of pain/adjustment has subsided completely. I suspect the reason of the symptoms in the area of temporal dithering/ FRC and/or font rendering. I've done a lot of research and tests and I think I can rule out a lot of other causes like PWM or LED hyper-sensitivity. Windows 7 is a save system for me.
If sitting in front of a save system and connection with VNC to a system which causes strain like Windows 10. The eyestrain/headache symptoms are triggered. I have problems to understand why? VNC just transfers compressed images, i set the refresh rate to 1 second, so in theory no dithering can be applied. If I connect to a system that is save, no symptoms are triggerd. So I can exclude that the VNC client tool itself perfoms dithering.
Any ideas?