DisplaysShouldNotBeTVs super informative, thank you very much. Based on your points, I'm leaning towards the display just being different than my work monitor as opposed to external factors. I will say my work environment is brightly lit, both with natural light and ceiling lighting (while my home setup is pretty dim), but the symptoms at home were so severe that I feel like it has to be the monitor itself.
This is also both frustrating and concerning, as my current monitor is from 2008 and if it craps out, I don't have a backup. I guess I'll have to keep searching..