JTL I have 2 configs: the one I use with no strain (or the least possible) is on HP Zbook G3, using Intel HD Graphics 530, with driver 20.19.15.4444 from 22-Apr-2016 (any newer drives strain), on Windows 8.1.
The other one is on HP Zbook G6 with Intel UDH Graphics 630 with the oldest driver I could find on HP's site, 25.20.100.6617 from 8-March-2019, on Windows LTSC 2019 build 17763.4252. This build has the strain lesser than the original win 10 PRO that it came with, maybe on par with Atlas OS and TinyOS, but still strong. The symptoms are dizzyness, tiredness, tired eyes and inability to read on paper soon after the use; in my case it did not lead to dried eyes even after a day of use, which is just the opposite of what most bad screens produce.
On the fist laptop I use ditherig 1.7 and on the second one 1.9. The only issue of the first one is that it reactivates dithering whenever the screen turns off (but not after sleep or shutdown).The later one is the oldest that works on that laptop and it is somewhat unstable; if I try newer version, the strain increases (mostly the ability to read on screen).