I have been trying for a few days now, and have installed:
I will not say it is as good as Windows 8.1 or Windows 10 2015 LTSB, but I am persistent in trying to find an alternative, as it is essential. This almost gets there, and I have not ruled out that it will. I will continue to use this as my main desktop for some time, as it is not obviously detrimental, alhough I have not ruled out the "small, cumulative" Linux eyestrain.
By the way, I tried the Xfce version of the newest Linux Mint and it was immediately uncomfortable. I am still trying MX Linux thanks to @Sunspark. It is not bad! I need to test it more, but it is taking a backseat to this recent potential success with Debian.
Sorry to keep tagging you @KM, but you mentioned Debian 11 Xfce and I feel that there is something here. I am using the default installed Firefox.
It would be really great if Linux held the way forward.
Here are my settings:

I believe this means sub-pixel anti-aliasing is disabled, and grayscale anti-aliasing is enabled.
Alternatively, MX Linux comes with the defaults:
Hinting: Slight
Sub-pixel order: RGB