Jack
I got you, looks like GA104 issue
My rtx3080 and rtx3080ti are GA102 LHR based chip, no issues in w10 1809. Rtx 2070s is TU104 chip, also OK.
Your Quadro RTX 4000 setup also unusable in win newer than 1809 (havent tested 1903), or you found something more to use?