WhisperingWind Processor: i5-12450H, Graphics: Intel UHD 48EU (Xe arch), RAM: 2 × DDR4 3200 8 GB Lexar LD4S08G32C22ST
I currently use mini-PC: i7 13700h + DDR5 4800 mhz KVR48S40BD8K2-64 + Iris XE 96UE with benq bl2420z (via HDMI to DVI cable). When I switched memory to KF556S40IB-16, I got strain. I also got strain with mini-PC 8845hz + 780m even with KVR48S40BD8K2-64 modules, but a little lower level comparing to default 5600 mhz modules. After experiments with registers, we with SunnyCove switch off all dithering settings in AMD, but 780m still strain
My hope was, Intel 12..14 gen CPUs works better with DDR5 gen ram, but your config shows it can be perfectly with DDR4 3200 without issues.
To be honest, 13700h + IRIS XE good with 4800 mhz DDR5 which have standart, not OC JEDEC timings (CL40). Lowering 5600 to 4800 timings with two different RAMs, didnt helps (only RAM with 4800 CL40 max is good). Your DDR4 also seems to have standart 3200 mhz timings (CL22).
The joke is, I tested laptop with same IRIS XE (13900h) but with LPDDR4 with win11 preinstalled, I play with it in 30 min and after leaving shop, got strain. So I dont really know, does lpddr4 matters in this case, or only screen pixel inversion/FRC (keeping in mind, IRIS XE is safe)