hayder1983 i have to test it for a week or two. If it doesn't work, i assume it is a body/physical issue for me!!
AMD GPU's
Should your problem not go away, send your card back and try glasses and eyedrops/healing ointment. It helped me reduce eye strain a lot. Dithering is still a problem for me, watching TV is still straining to me, but using the PC is much better now. I just have 0,75 dioptrin on each eye, still made a huge difference.
You could also try lenses, because it would be cheaper to try. They cost like under 20$ for 30 lenses.
hayder1983 I've just tried to play with contrast both in adrenalin and monitor, look like vivid gaming doing something with gamma i guess, completly different results. I'm trying to adjust green, much green in some videos and artifacts on black shades.
WeinTrust i think it is much more contrast and different gamma, which will oversaturate a lot colors and change gamma for all colors. I cant find a sweet point that way.
I am pretty sure dithering is not off, even with 6bit colors. I can see the dithering on grey and white. Dont buy a new AMD card just to turn off dithering, it doesnt work. Sorry 
reaganry You are right. Look it does calmer to you?
The option right below(GPU-Skalierung, dont know the english name) seems to affect dither too, at least on my old LG. I am using it on native resolution. You can use them both at once. Not sure why this makes a difference, but it looks like it does.
I just changed the monitor driver for my super old LG monitor and i am using the "PnP-Monitor" now. It is different now, still dithering. AMD Pro driver still knows what monitor is connected.
I just tried using different color scheme on my browser with colors of the 6bit palette(see below). I have to test it a few days, so i dont imagine things…
https://lospec.com/palette-list/6-bit-rgb
I dont think anything in the settings of driver will really disable it. It seems dithering is everywhere. Steam deck is supposed to have no dithering at all(not sure) and it has windows emulated on it. I will try to plug it on an Monitor in a few days( not today, my brain is overheating) and see for my self. I could live with Steam deck+Monitor with integrated docking station as an Home PC. I have everything at home right now, just need the time to do it 
Just tried Super resolution and on the highest(!) resolution available(2,28xnative resolution). On similar scaling for some reason reading text is easier on the eyes. Not sure why, it is different kind of sharpness? If reading gets easier, eye sore should get bit less. Thanks for the suggestion
hayder1983 I have a dock for my steam deck but unfortunately at the current time I can only use hdmi with it, not displayport yet (waiting on an update, none of my dp adapters work with it). I do think I can see frc dithering on desktop mode, but the thing is, I'm using a monitor that ALREADY has frc dithering.. so I can't easily tell if it's both the panel and the driver at the same time or just one. I'm fine with the purchase, it isn't perfect but it is usable and I don't feel the need to get rid of it. Will be interesting to see what updates to it (kernel, driver, etc.) do.
I still prefer using my older PC as a desktop, I don't use the SD as a desktop even tho it's more powerful. I'll re-consider down the road when support for Windows dual-boot is better.
I contacted AMD earlier this year and spoke to a rep that consulted engineering. I was told that the 6500xt (I specifically asked about that card as I’m interested in it) does not have temporal dithering on. I read dithering in this thread quite a bit and sometimes it’s hard to tell if people are referring to static or temporal. I plan to buy a 6500xt before they EoL and add it to my next build whenever that should be.
This is a super interesting piece of information. If the 6500xt is really dithering free, that would be an option, but it is more or less super weak in games. Well, that means i would need a multi-PC setup 
.
- Edited
Ok, this strangely helped. I am using a super old LG monitor. There is no icc profil for it anymore, so i took an icc profil of a similar LG monitor. That was like 2 weeks ago. Now i deleted EVERY icc profil.
Now white is calm. Dithering is less or gone, not sure, at least for 6bit white.
EDIT: I have color tempeture control on "off" setting.
- Edited
hayder1983 is it really?? I thought it was supposed to be sufficient…. I’m still currently using an Nvidia 1770
Correction. It was the 6950 I inquired about. Sorry.
- Edited
Clokwork No, sorry. I have "crushed whites" with very high contrast, therefor i couldnt see it on white. My AMD card is unusable to me right now, i get super hard cramps super fast. My body knows it dislikes it.. Right now i am writing from my Steam deck with docking station and in desktop mode(external screen only). If it uses dithering it is less aggressive than my 6600xt(hundreds of € down the drain). I have to try for a few weeks if this is ok for me. Otherwise i need a old ditherfree Nvidia too.
At the moment playing video games is not possible for me, my eyes are cramping on my ATI, mildly cramping on my work laptop(external screen only) and steam deck seems ok up till now.
EDIT No Steam deck is dithering
@hayder1983 , to what type of dithering are you referring? Temporal or static? I believe we get very different symptoms from screens. I suffer from neurological issues regarding certain screens. Symptoms like inability to focus on any particular part of a screen, dizziness, vertigo…
My symptoms are very new to me, last christmas i could do everything, watch TV, play PC Games. Now my eyes dry out superfast, White looks often too sharp, and the screen looks "busy". I think that is dithering and i cant see it on my TV or my phone. Sometimes i get nausea, my BenQ VA Panel is to high contrast, even on lowest setting, killing my eyes fast. IPS and TN Panels are ok.
I just bought a new gaming PC in June, build it my self and now i have all these symptoms, so i naturally think it is the new PC. Tested an Nvidia, had bad symptoms(only in the eyes), colors were super strange, then send it back, bought the 6600xt. Tested 10+ Monitors. It is super strange. Sometimes everything was ok, then all went to hell again. Now i will try to not use my home PC and test Steam Deck as an Home PC, just to be sure it isnt something related to the 6600xt. The screen still looks busy, but i dont have a better device now and my eyes didnt twitch and i didnt get nausea(until now).
I will try to do everything with low brightness on my monitor. When my symptoms are gone somehow, i know it might just be my new PC, not any monitor.
I actually tested sth, that noone should test, because (i think) you can actually damage your monitor with this. In custom resolution you can change the timing of your GPU/Monitor. It was set to CVT-RB. I tried it without RB and somehow i nearly vomitted from looking at the screen. Not sure why. Perhaps there is sth with my brain, but i prefer testing Steam deck before going to the doctor, because they just know what i tell them.
Additionaly when i dont use the PC for a few weeks, which happened just because i was on holiday, everything was fine. Every screen was fine. No eye pain, no eye drops, watching TV with my son was ok. After that massive eye pain on EVERY screen, but it was my eyes overreacting.
If you are at peace with you current GPU, then dont upgrade or at least keep every old GPU/mainboard/monitor, so you can downgrade again.
What does you help when your symptoms act up? Or is it like always there?
- Edited
hayder1983 Don't worry, you won't damage your monitor by changing the modeline you send the display, whether GTF, CVT, CVT-RB, CVT-RBv2, CEA861, etc. If the modeline is out of spec, the monitor will simply go black and put up a dialog saying incorrect input received. I've played with all of those along with different inputs, and I do see differences, and you are able to change the refresh incrementally to dial in the rate you need via this method, but it's a lot of work with very diminishing returns, it's best done for when you want exact video rates like 23.976 etc.
With the dock you have for the SD are you using HDMI or Displayport? I have the Valve dock and with the current software/firmware, displayport output is borked, so I am only able to use the HDMI output.. except my only port is occupied, so I'm actually sending it to the DVI port (which is the same video signal, no active adapter needed). I agree it isn't perfect, but it is playable. I mean, I've put like 100 hours into the SD already, though not with 3D games. By our standards here, this is considered a success.
You can expect changes.. 3.4 will have a kernel update and a new version of mesa, and Valve will have to push a firmware update to the dock because so many people can't connect their displays. And of course, right now desktop mode is using X11 (I am fine with this) but maybe next year it will be Wayland. Gaming mode interface is using Wayland, desktop mode is not.
Here is something you can try if you feel up to it.. get a SD card (or even better, an external USB drive), install Windows to the SD card. Boot into the SD card. Both 10 and 11 will work. See how it is. I don't do this, but a fair few people do because some games need anti-cheat. You can read this sub to figure it out, https://old.reddit.com/r/WindowsOnDeck/