This monitor is fantastic. There are no flicker symptoms on a good setup.
It does pass through strain from bad OS, GPU and software as expected.
However, it eliminates a major factor in eyestrain which is spectrum and flicker. To otherwise eliminate these issues you would need to find a Quantum Dot monitor or TV with low ripple and pixel inversion, etc.
I cannot recommend it enough if you have a good setup you want to amplify.
If you are trying to make a bad setup tolerable e-ink MAY be a better option (unsure, @ensete already mentioned modern Windows causes him strain on e-ink, which is very concerning).
I still need to set up a proper lighting situation for evenings though, which I mentioned in some other posts pertaining to LED strip lighting.
Having a good setup, I only find myself turning to e-ink when it is dark. E-ink is legible with much less light (I have NOT messed with the settings on the Sun Vision yet).