Maxx I've tried ditherig in multiple computers and it does not make any difference.
ditherig worked for me on 3rd gen intel i7 (ivy bridge) laptop with intel hd 4000 and Windows 8.1, huge improvement. running it reduces the screen ALL the way to true 6-bit
one day i had accidentally forgot to run it, i didn't even know that it wasn't running, but suddenly i was having a lot of trouble processing repeating vertical information on the screen (to be specific, the checkboxes on Gmail web) and feeling really tired. eventually realized i forgot to open ditherig, boom, entirely fixed screen became 100% comfortable again and i could finally see "all of the things repeating all at the same time in perfect alignment".
ditherig WORKS on that machine, no placebo — absolutely noticeable and real improvement.
but i agree it doesn't work at all on most other computers very flaky on anything newer than like 2015 lol
thankfully it worked on my old laptop though