Maxx We will never solve this issue if it is completely individual how each person's eyes get irritated by each device.
I consider the problem there is quantifying what exactly is different between display panels and potential other factors like alleged GPU or software rendering issues and how that contributes to eyestrain is a problem of itself.
As I wrote recently in another thread about investigations into alleged temporal dithering/GPU rendering issues between drivers.
[Sometime] in the past someone complained on the Intel forums that allegedly a model of laptop with one version of the driver did not cause eyestrain while a newer version did. And Intel (IMO) used a flawed methodology because they sent two identical laptops that supposedly only differed by the driver version to a testing lab which measured for PWM, blue light and other "obvious" factors and when there was no difference they closed the case on their end. It's easy to get upset at this but what I think the issue is trying to engage with development of any solution is without a clear "cause and effect" relationship there are many different things that cause the vague description of "eyestrain" and unless someone at these tech companies is REALLY bored or personally experiences the issue, don't expect to be investigated and solved by them.
Not sure I linked this before, but if this review unit has the same panel as yours Notebookcheck tested they tested several brightness and color properties of the display as compared to others. Not sure how relevant that is towards whatever causes your issue.