On my iPhone 6s I have always used lowest brightness and when Night Shift became available I enabled that 24/7 and at it's warmest setting. There was an option in accessibility to 'Reduce White Point' but the effect was so insignificant as to make little difference.
The display was still way too bright. Recently I revisited the 'Reduce White Point' option and found that there is a sliding scale and you can really dial down the harshness of the light (believe this was introduced in 10.3). It's a huge improvement and I can use the phone for short periods to shoot a text or short email whereas previously I would not use it except to make calls which I did with voice commands.
It's still not a comfortable display and I can't get comfortable using as it can cause eyegraines which I usually associate with PWM but iPhone 6s does not use PWM..
Either way this new slider on 'Reduce White Point' is a big improvement.