My read is that dithering causing my eye strain. I can recommend you to the HTC 10 (LCD). It is the latest device I can use without strain. The successor HTC U11 (LED) causing strain. The fact that using old AMOLED devices like the HTC One S not causing strain hints me that PWM should not be my problem. I tried different blue light filtering screen protectors and the Skinomi film on strain devices, none of them improve the situation.
Device history (no strain): HTC Desire, HTC One S (AMOLED), HTC One X, HTC One, HTC M8, HTC 10
Device testet (strain): Samsung S7 (AMOLED), HTC U11 (LCD), BQ X2 (LCD), Google Pixel XL (AMOLED), Google Pixel 2 (AMOLED), Google Pixel 2 XL (POLED), Huawei P10 (LCD), Google Pixel C (LCD), Samsung Tab 2 (AMOLED), iPhone X (AMOLED)