Stephan-M Yes, I have tried different Linux Distros a few years ago and was happier with them. The eyestrain was gone, since Linux is programmed to process the image output differently.
I've had the opposite experience, a ThinkPad with an old TN display which is otherwise good on Windows (and best with older Windows like LTSB 2015), instantly becomes unusable when booting into multiple Linux distros, no matter if its an old Linux version from 2018 or a current one. Also tried both GNOME and MATE desktop environments, compositor on/off, and both Wayland and X, but all of those still managed to mess up what is otherwise a really good TN display on Windows. Still had problems even when Linux graphics acceleration was turned off.
Same with another old laptop I have (which has one of the only IPS displays I've used that actually works for me), it's very usable in Windows 8.1, but immediately causes strain in Ubuntu 24.04. Interestingly I had a somewhat better experience with Arch Linux, but still not as good as Windows 8.1.
I'm pretty sure though that the root cause is how the Linux kernel interacts with the Intel graphics chipset. Linux issues on this forum seem to be heavily tied to Intel integrated graphics devices. It seems more likely for dedicated GPU users to have a chance of a better experience on Linux.