Well I took the plunge and bought myself a Nintendo Switch, and I'm very happy to report that I don't seem to have any issues with it so far! I did the initial setup for 2 hours on the handheld device without any "LED headache" or terrible pain behind my eyes like I've described with almost every other type of LED monitor. Remember, I'm the guy that will have a really bad headache and aching eyeballs within seconds/minutes of looking at LED-backlit computer monitors in the office.
While this is very exciting for my new purchase (especially as a die-hard Nintendo fan), this almost opens up more questions than it answers. I have not been able to tolerate any modern displays for quite some time now (chiefly LED). Why am I able to tolerate this one? Is the handheld display not an LED perhaps?
I do have one issue with my Switch though, but thankfully it's purely technical and not health related! When I went to dock the Switch to my TV for the first time, the screen constantly trembles, is slightly zoomed-in and off center, and there are flickering lines that appear on the screen. This is on my old 40" Samsung Series 6 LCD TV that I bought 10 years ago. I get slightly better results when I try different HDMI ports (HDMI4 on the side works the best for some reason).
These things do go away if I go in the Switch settings and downgrade the output from "Automatic" or "1080p" down to 720p, but as you can imagine, it's not the most ideal workaround because it doesn't look at good