Adding my experiences to the wider discussion here. I'm A-OK with my Plasma TV and I'm OK with my Dell 2407/2410 or similar CCFL screens on a Nvidia 970 (and AMD 6950), as well as my 2013 MacBook Pro's IPS screen.
Otherwise several new LCD TVs, most iPads and iPhones (haven't tried OLED), various laptops, and several new computer monitors (high refresh, low blue, AMVA, IPS), Xbox One, and 980, 980Ti, 1070, 1080 cards all give me eye strain. At this point I'm thinking wow - it's both the screens AND the hardware that's driving them. Realising it was also the video cards was really a sad moment. But then you add the new version of Chrome, Firefox and Prepar3D Flight Sim V4 that ALSO give me the same eye strain and the whole situation gets twice as convoluted, and frustrating.
Now, I really don't know what to make of it. Screens do it. Video cards do it. And now windows (part or full screen) can do it too. For the life of me I cannot decide if it's blue light, PWM, dithering or something else. Right now, my money's on dithering or maybe something else. And you know it's damned expensive buying gear to TRY only to have to on-sell it at a loss. Where I live we don't have easy try-before-you-buy or money back returns (except Apple - which I've taken up on a couple of iPad tests).
And yes I've had my eyes tested, blah blah blah, and I counter that by saying - "I can watch/use my older hardware for hours with no problems at all - so it's not my eyes!"
Personally, all I really want right now is to be able to go out and buy a more powerful GPU for my flight sims - I can live with 24" screen(s). But then if I ever change job... I guess I'll need to buy this MacBook Pro 2013 that I'm happily using - from my current employers.