All I can really say is that its worth trying different colour formats on the cards you have if you are having a problem. Whilst my gtx 660 does not dither on full RGB, I can't say if it will be the same for other Nvidia cards. But, I personally would be fairly confident that if I bought a new card I'd be able to find a setting that did not dither.
The other, and in my opinion, more important conclusion is that dithering frequency depends upon the colour being displayed. I think this is why people have problems when software updates or changes, steam and chrome for example. The software itself isn't dithering, but if the colours have been changed slightly that will affect how the GPU is dithering and might produce symptoms.