I am glad I found this forum. I am going through the same thing and it's driving me mad.
There is undeniably something happening in newer monitor and possibly GPU's that is increasing eye strain. There are some older monitors that can cause eye strain, but for the most part I can agree that the older the monitor, the less the eye strain. Specifically the early LCD's are the best at reducing eye strain. I am currently using a 2004 Dell LCD 1440x900 resolution VGA ONLY. I had spoken to a tech friend who said it may be the color, increase color clarity causing eye strain due to eyes focusing on brighter colors. I am currently using a MacBook Air with everything set to black and white, brightness all the way down, and STILL have eye strain. I also have an LG Ultragear OLED, which Is an amazing monitor, but I can't use it for long.
I am able to use these newer monitors for a few hours, but I had redness puffiness and sore eye bags right after. I Stopped using the newer monitors and went back to my VGA dell, puffiness almost gone completely much better on my eyes.
I also have DVI/HDMI monitors from 2008, 2012, 2015 and 2020. Different connections, different inputs, different screen sizes, different panels, different technologies etc. etc. The only common correlation : Newer is worse on the eyes. I don't have a CRT to compare, but I think these early LCD's were extremely good at reducing eye strain. They competed with CRT's which had much more vivid and fluid images, but they helped with office work and long time use. To make these Flat panels better, something changed and got worse over time, at least for me and looks like some of you guys too.
I basically use my VGA dell unless I want to game competitively, it's the only way to avoid eye strain. I really have no idea what changed, does anyone know?