idk which "strain" case is your… when I thought the polarisation is the issue, I checked all displays around me - safe were horisontal and vertical, one phone was round polarisation. So, personally for me, polarisation is not issue
Last week I checked 3 replacement panel for my laptop, but each of them have defects.
lp173wf4-spf5: opple4 shows no PWM ( 3 khz ) but I felt strain from the laptop's BIOS loading moment. Pixel invertion had a chess pattern. 6-bit panel, great brightness (upto 300nits), a bit red color lack, 7000k temperature
b173han01.8 - great brightness (upto 300nits), no red color lack, 6-bit + FRC, no PWM (40khz, but need adoptation), green channel had epic high value, as when I seen another white screen, it looked red ! 6700k temperature. Chess pattern of pixel invertion
b173han01.0 - bad brightness (upto 140 nits), no red color lack, EDID show it is 6-bit but when I put 8-bit on it, it starts to FRC, excellent temperature ( 6500k ), no PWM - most calm panel of those 3, no eyes adaptation need at all. Chess pattern of pixel invertion