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Gurm Same thing here, I had a Moto G on Lollipop, no issues, the Marshmellow update came down, and I got severe eye strain. Something in the OS altered the way the video hardware is driving the screen. I have not moved any of my PC's off Windows 7 so I cant speak to 10
Just another FYI, I would suggest trying those specific brands (TechArmor or Skinomi). I keep a running list and most screen protectors do not help at all. I have emailed both companies trying to determine what makes their protectors different, or find out what exactly they filter out, but cannot get an answer from them.