I am back with an update after 18 months. The Asus Zephyrus G14 mentioned in the OP is still not comfortable for me so I use it only sparingly: no more than 30 minutes / day. I switched to a Samsung Galaxy tab S7 as my primary computing device - it's perfectly comfortable for all-day use. I also upgraded my phone to an iPhone 11 and that is perfectly usable as well.
I am on the hunt for a workable laptop again and am currently testing out two laptops. They both have MUX switch, NVIDIA discrete graphics cards, and screens without PWM according to review sites.
Lenovo Slim 7 Pro X (Model 82V20003US from Costco in USA):
Windows 11 Home
AMD Ryzen 9 6900HS (8-Core) Processor
14.5" Touchscreen IPS sRGB 3K (3072 x 1920) 120Hz Display
NVIDIA® GeForce RTX™ 3050, 4GB
MSI GE76 Raider (Model Raider GE76 12UE-456 from Costco in USA):
Windows 11 Home
12th Gen Intel Core i7-12700H Processor
17.3" Thin Bezel IPS FHD (1920 x 1080) 144Hz Display
NVIDIA® GeForce RTX 3060 Graphics, 6GB
My reasoning for testing these two quite different laptops is to compare the effects of:
High resolution panel vs low resolution panel
Glossy panel (Lenovo) v/s matte panel
14.5" screen v/s 17" screen (test effect of viewing distance)
AMD v/s Intel CPU (should not matter in theory since I am going to use discrete graphics)
The Lenovo looked more promising initially so I am doing a deeper test on it first with the following software modifications:
NVIDIA Control Panel: display mode set to "NVIDIA GPU Only", native resolution and max frame rate (120 Hz), use NVIDIA color settings with 8 bpc output color depth, no scaling, and G-sync enabled for full-screen and windowed mode.
Registry update to disable dithering (https://www.youtube.com/watch?v=DOGVm1tjsT4), used the "turn off dithering binary key db,01,00,00,10,00,00,00,02,00,01,04,f3,00,00,00"
Windows settings: Night Light on and set to 50%, increased font size to 150%, tuned "ClearType" text, scaling remained at default 200%.
The Lenovo appears to be significantly more comfortable than the Zephyrus G14, but unfortunately my eyes are already strained from doing the initial setup yesterday. I need to let my eyes rest for a day before resuming the evaluation. I will post an update in a few days.