So I found a possible bug with the Nvidia X Server Settings application. On my system I if I set Dithering to Disabled and then save the .nvidia-settings-rc file to /home, it doesn't set the Dithering option correctly. I had to open the file and for each line that said "Dithering=0" change it to "Dithering=2". 0 = Auto which usually means enabled. 1 = Enabled. 2 = Disabled. I then added the following command to my startup: "nvidia-settings --load-config-only". Logged out and back in and than ran the following command: "nvidia-settings -q CurrentDithering". The result now shows dithering is definitely disabled. You can also run the command "nvidia-settings -q Dithering" to make sure the value is 2 (for Disabled).
Now when I open Nvidia X Server Settings, the setting remains on Disabled.
Now as far as did it fix my issue? It's too late for me to test right now for a prolonged session, so I'll test tomorrow when I wake up and see if it helps.